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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
10.91
Human Site:
Y238
Identified Species:
24
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
Y238
Q
N
G
P
R
G
L
Y
A
F
G
A
E
R
G
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
P238
G
Q
N
G
P
R
G
P
F
G
A
E
R
G
N
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
R196
H
S
W
S
D
A
L
R
S
F
S
G
G
Q
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
Y238
Q
G
G
P
Q
G
L
Y
A
F
G
A
Q
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
Y239
Q
R
G
P
R
G
I
Y
A
F
G
A
K
R
G
Chicken
Gallus gallus
XP_425053
1523
173782
Y219
Q
G
G
L
R
G
I
Y
D
L
G
N
A
W
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
K141
D
W
D
T
S
T
G
K
S
P
N
N
P
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
L209
K
M
L
S
P
E
R
L
F
L
L
G
D
P
R
Honey Bee
Apis mellifera
XP_624355
1492
172466
L223
R
M
L
S
P
E
R
L
Y
L
L
G
D
P
R
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
F229
L
M
S
P
D
R
L
F
M
L
G
D
S
R
V
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
R314
P
I
A
E
G
A
A
R
L
Q
R
S
E
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
0
13.3
N.A.
N.A.
N.A.
80
N.A.
80
46.6
N.A.
6.6
N.A.
0
0
26.6
13.3
P-Site Similarity:
100
0
33.3
N.A.
N.A.
N.A.
93.3
N.A.
93.3
53.3
N.A.
13.3
N.A.
13.3
13.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
19
10
0
28
0
10
28
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
19
0
0
0
10
0
0
10
19
0
0
% D
% Glu:
0
0
0
10
0
19
0
0
0
0
0
10
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
19
37
0
0
0
0
10
% F
% Gly:
10
19
37
10
10
37
19
0
0
10
46
28
10
10
37
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
19
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
10
0
19
10
0
0
37
19
10
37
19
0
0
0
10
% L
% Met:
0
28
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
10
19
0
0
10
% N
% Pro:
10
0
0
37
28
0
0
10
0
10
0
0
10
19
0
% P
% Gln:
37
10
0
0
10
0
0
0
0
10
0
0
10
10
0
% Q
% Arg:
10
10
0
0
28
19
19
19
0
0
10
0
10
55
19
% R
% Ser:
0
10
10
28
10
0
0
0
19
0
10
10
10
0
0
% S
% Thr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
37
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _